The FDA reports note that many of the kratom-associated deaths appeared to have resulted from adulterated products or taking kratom with other potent substances, including illicit drugs, opioids, benzodiazepines, alcohol, gabapentin, and over-the-counter medications, such as cough syrup. Also, there have been some reports of kratom packaged as dietary supplements or dietary ingredients that were laced with other compounds that caused deaths.
People should check with their health care providers about the safety of mixing kratom with other medicines. Like other drugs with opioid-like effects, kratom might cause dependence, which means users will feel physical withdrawal symptoms when they stop taking the drug. Some users have reported becoming addicted to kratom. Withdrawal symptoms include:. There are no specific medical treatments for kratom addiction. Some people seeking treatment have found behavioral therapy to be helpful.
Scientists need more research to determine how effective this treatment option is. In recent years, some people have used kratom as an herbal alternative to medical treatment in attempts to control withdrawal symptoms and cravings caused by addiction to opioids or to other addictive substances such as alcohol. Contamination and adulteration with other drugs, herbs, and substances are possible.
For instance, in at least Americans became sick after taking kratom tainted with salmonella. Kratom comes with a risk of tolerance, dependence, and withdrawal. People who use kratom can build a tolerance , or the need to use more to achieve the desired effect, and experience symptoms of withdrawal when they stop taking the drug. More research is needed to determine the exact half-life of kratom. Like other substances, how long kratom stays in your system will depend on the following factors:.
The DEA states that kratom abuse can lead to addiction and can result in psychotic symptoms, including hallucinations, delusion, and confusion. Not everyone will experience addiction in the same way, but there are several hallmark signs and symptoms, including tolerance, dependence, and withdrawal. Other common signs of addiction include:. People who take large doses of kratom several times per day have an increased risk of moderate to severe withdrawal symptoms.
In general, however, withdrawal symptoms are milder in comparison to opioid withdrawal and may include:. Living with pain isn't easy. If you live with pain, you may already be all too familiar with the profound effect it can have on your quality of life. For more mental health resources, see our National Helpline Database.
If you are considering trying kratom, you should speak with your healthcare provider first. Some pain clinics utilize complementary and alternative therapies in conjunction with traditional medical approaches for pain treatment and management. For example, mindfulness and other mind-body practices may help some people remain pain-controlled despite the challenges of everyday life. If you've been using kratom to self-medicate and have noticed that it has begun to take over your life, don't wait to get help.
A trusted healthcare professional can help guide you toward the path of recovery. Learn the best ways to manage stress and negativity in your life. Food and Drug Administration. Published February 6, Kratom Mitragyna speciosa dependence, withdrawal symptoms and craving in regular users. Drug Alcohol Depend. The informal use of ketum Mitragyna speciosa for opioid withdrawal in the northern states of peninsular Malaysia and implications for drug substitution therapy.
Int J Drug Policy. J Med Chem. White CM. Pharmacologic and clinical assessment of kratom: An update. Am J Health Syst Pharm. Drug Enforcement Administration. The way that mitragynine works is very complex.
It stimulates opioid receptors weakly but also interacts with serotonin and norepinephrine receptors. Painkilling effects of mitragynine is more pronounced when taken orally as opposed to injected. This suggests an additional metabolite is produced during first-pass metabolism that may contribute to the painkilling effects. Injecting mitragynine straight into the brain of mice produced a similar painkilling effect as when taken orally.
This also suggests that further metabolism may actually take place in the brain itself. The medical use of kratom is a very contentious subject within the medical community.
There are those who believe that kratom can offer minor therapeutic benefits as a tool in certain health treatments. Others are much more cautious, citing the many risks associated with kratom. Kratom has already resulted in deaths through overdose. It is clear that it does have a potential for abuse as many treatment facilities can attest.
Much more research is needed before a definitive and factually supported position can be taken by the medical community and government. The Summit Wellness Group is located in Metro Atlanta, Georgia and all of your calls will be directed to one of our local staff members. Our sincere passion is helping people overcome addiction to live full, meaningful, and healthy lives.
Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Kratom Mitragyna speciosa is a tree in the coffee family. Traditionally, people have:. This is because two of the compounds in kratom mitragynine and 7-hydroxymitragynine interact with opioid receptors in your brain. Medical communities now try to shy away from opioid use for pain , so many patients who previously relied on them no longer can.
Scrambling to find alternatives, some people turn to kratom, which is a compelling replacement because it has similar pain-relieving effects. A: Traditionally, people drink kratom as a tea or chew its leaves. Kratom can also be found in resins, extracts and tinctures.
0コメント